[{"@context":"https:\/\/schema.org\/","@type":"Article","@id":"https:\/\/www.dorton.cz\/endometrioza-vedci-nasli-pricinu-obrovske-bolesti-je-to-nadeje-pro-miliony-zen\/#Article","mainEntityOfPage":"https:\/\/www.dorton.cz\/endometrioza-vedci-nasli-pricinu-obrovske-bolesti-je-to-nadeje-pro-miliony-zen\/","headline":"Endometri\u00f3za: v\u011bdci na\u0161li p\u0159\u00ed\u010dinu obrovsk\u00e9 bolesti. Je to nad\u011bje pro miliony \u017een?","name":"Endometri\u00f3za: v\u011bdci na\u0161li p\u0159\u00ed\u010dinu obrovsk\u00e9 bolesti. Je to nad\u011bje pro miliony \u017een?","description":"V\u00fdsledky nov\u00e9ho v\u00fdzkumu ve Velk\u00e9 Brit\u00e1nii mohou b\u00fdt nad\u011bj\u00ed pro nemocn\u00e9. Pro\u010d endometri\u00f3za zp\u016fsobuje takovou nep\u0159edstavitelnou bolest? Endometri\u00f3za: co je to za nemoc? Endometri\u00f3za je onemocn\u011bn\u00ed, p\u0159i kter\u00e9m se endometrium objevuje nejen tam, kde by m\u011blo, tj. v d\u011bloze. Endometri\u00e1ln\u00ed lo\u017eiska se vyskytuj\u00ed nap\u0159\u00edklad na […]","datePublished":"2020-01-09","dateModified":"2023-04-30","author":{"@type":"Person","@id":"https:\/\/www.dorton.cz\/author\/#Person","name":"","url":"https:\/\/www.dorton.cz\/author\/","identifier":1,"image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/06473a178d94fb830b46e277369729e9534f2612e261ec2f1ee96b672ef473e2?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/06473a178d94fb830b46e277369729e9534f2612e261ec2f1ee96b672ef473e2?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"dorton.cz","logo":{"@type":"ImageObject","@id":"\/logo.png","url":"\/logo.png","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/www.dorton.cz\/wp-content\/uploads\/img_a367271_w4276_t1579766290.jpg","url":"https:\/\/www.dorton.cz\/wp-content\/uploads\/img_a367271_w4276_t1579766290.jpg","height":0,"width":0},"url":"https:\/\/www.dorton.cz\/endometrioza-vedci-nasli-pricinu-obrovske-bolesti-je-to-nadeje-pro-miliony-zen\/","about":["\u017deny"],"wordCount":455,"articleBody":"V\u00fdsledky nov\u00e9ho v\u00fdzkumu ve Velk\u00e9 Brit\u00e1nii mohou b\u00fdt nad\u011bj\u00ed pro nemocn\u00e9. Pro\u010d endometri\u00f3za zp\u016fsobuje takovou nep\u0159edstavitelnou bolest?   Endometri\u00f3za: co je to za nemoc?  Endometri\u00f3za je onemocn\u011bn\u00ed, p\u0159i kter\u00e9m se endometrium objevuje nejen tam, kde by m\u011blo, tj. v d\u011bloze. Endometri\u00e1ln\u00ed lo\u017eiska se vyskytuj\u00ed nap\u0159\u00edklad na vejcovodech, vaje\u010dnic\u00edch, mo\u010dov\u00e9m m\u011bch\u00fd\u0159i, a dokonce ve st\u0159evech nebo pl\u00edc\u00edch. B\u011bhem menstruace hormony zp\u016fsobuj\u00ed, \u017ee se sliznice odlupuje, co\u017e se projevuje krv\u00e1cen\u00edm. Proto\u017ee krev nahromad\u011bn\u00e1 vn\u011b d\u011blohy nem\u00e1 \u017e\u00e1dn\u00fd v\u00fdtok, vytv\u00e1\u0159ej\u00ed se cysty a z\u00e1n\u011bt. A\u010dkoli endometri\u00f3za nen\u00ed p\u0159\u00edm\u00fdm ohro\u017een\u00edm \u017eivota \u017eeny, m\u016f\u017ee to v\u00e9st k \u0159ad\u011b zdravotn\u00edch probl\u00e9m\u016f, zejm\u00e9na k neplodnosti, poruch\u00e1m imunitn\u00edho syst\u00e9mu a bolestem v rozsahu, kter\u00fd m\u016f\u017ee dokonce v\u00e9st k mdlob\u00e1m. V sou\u010dasn\u00e9 dob\u011b l\u00e9ka\u0159i dosud nevyvinuli uspokojivou l\u00e9\u010dbu endometri\u00f3zy. Obvykle se pou\u017e\u00edv\u00e1 chirurgick\u00e9 odstran\u011bn\u00ed patologick\u00fdch lo\u017eisek a hormon\u00e1ln\u00ed terapie. Prvn\u00ed z t\u011bchto metod je invazivn\u00ed a nezabra\u0148uje progresi onemocn\u011bn\u00ed. Druh\u00fd zp\u016fsobuje \u0159adu vedlej\u0161\u00edch \u00fa\u010dink\u016f. \u017d\u00e1dn\u00fd z nich nep\u0159in\u00e1\u0161\u00ed dlouhodobou \u00falevu od bolesti. V\u011bdeck\u00e9 zpr\u00e1vy ze Spojen\u00e9ho kr\u00e1lovstv\u00ed v\u0161ak nazna\u010duj\u00ed, \u017ee se tato situace brzy zm\u011bn\u00ed.  Co je p\u0159\u00ed\u010dinou obrovsk\u00e9 bolesti?  V\u00fdsledky v\u00fdzkumu proveden\u00e9ho na University of Warwick v Anglii ukazuj\u00ed, \u017ee p\u0159\u00ed\u010dinou obrovsk\u00e9 bolesti p\u0159i endometri\u00f3ze m\u016f\u017ee b\u00fdt n\u00e1\u0161 imunitn\u00ed syst\u00e9m. V\u011bdci zjistili, \u017ee endometri\u00e1ln\u00ed lo\u017eiska maj\u00ed zv\u00fd\u0161en\u00e9 mno\u017estv\u00ed makrof\u00e1g\u016f, jednoho z typ\u016f b\u00edl\u00fdch krvinek. Srdcem probl\u00e9mu je to, \u017ee akumuluj\u00edc\u00ed slizn\u00ed makrof\u00e1gy produkuj\u00ed inzul\u00ednov\u00fd r\u016fstov\u00fd faktor IGF-1, kter\u00fd stimuluje r\u016fst a aktivitu nervov\u00e9 tk\u00e1n\u011b. To zase zvy\u0161uje va\u0161i citlivost na bolest. Jak dosp\u011bli v\u011bdci k tomuto z\u00e1v\u011bru? V experimentu byla pou\u017eita um\u011bl\u00e1 kultura t\u011bchto makrof\u00e1g\u016f. Uk\u00e1zalo se, \u017ee po jejich um\u00edst\u011bn\u00ed do kultury nervov\u00fdch bun\u011bk byly jasn\u011b aktivov\u00e1ny. Krom\u011b toho byla vy\u0161et\u0159ena peritone\u00e1ln\u00ed tekutina od zdrav\u00fdch a nemocn\u00fdch \u017een. V\u00fdsledky testu potvrdily, \u017ee \u017eeny trp\u00edc\u00ed endometri\u00f3zou maj\u00ed zv\u00fd\u0161en\u00e9 hladiny faktoru IGF-1. Dr. Erin Greaves, hlavn\u00ed autor studie, se domn\u00edv\u00e1, \u017ee pokud se nau\u010d\u00edme detekovat \u201enemocn\u00e9\u201c makrof\u00e1gy \u2013 a pak je zac\u00edl\u00edme na n\u011b, pak m\u016f\u017ee doj\u00edt ke skute\u010dn\u00e9mu pr\u016flomu v l\u00e9\u010db\u011b endometri\u00f3zy.                                                                                                                                                                                                                                                                                                                                                                                         4\/5 - (10 votes)        "},{"@context":"https:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Endometri\u00f3za: v\u011bdci na\u0161li p\u0159\u00ed\u010dinu obrovsk\u00e9 bolesti. Je to nad\u011bje pro miliony \u017een?","item":"https:\/\/www.dorton.cz\/endometrioza-vedci-nasli-pricinu-obrovske-bolesti-je-to-nadeje-pro-miliony-zen\/#breadcrumbitem"}]}]